TGF-β3 Stimulates Stromal Matrix Assembly by Human Corneal Keratocyte-Like Cells
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چکیده
منابع مشابه
Twist2: role in corneal stromal keratocyte proliferation and corneal thickness.
PURPOSE Twist2 is a member of a family of bHLH transcription factors critical for normal mesenchymal proliferation and differentiation. In this study, the authors analyzed the role of Twist2 in the eye and cornea through examination of a Twist2 loss-of-function mouse mutant. METHODS Twist2 expression during eye development in the mouse was investigated using RT-PCR and mRNA slide in situ hybr...
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Corneal diseases such as keratoconus represent a relatively common disorder in the human population. However, treatment is restricted to corneal transplantation, which only occurs in the most advanced cases. Cell based therapies may offer an alternative approach given that the eye is amenable to such treatments and corneal diseases like keratoconus have been associated specifically with the dea...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2013
ISSN: 1552-5783
DOI: 10.1167/iovs.13-12861